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Base Year: 2024
Companies covered: 15
Tables & Figures: 190
Countries covered: 19
Pages: 140
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Organ-on-chips Market
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Organ-on-chips Market Size
The global organ-on-chips market was valued at USD 147 million in 2024. The market is expected to reach from USD 201.5 million in 2025 to USD 2.1 billion in 2034, growing at a CAGR of 29.7% during the forecast period. The high market growth is attributed to the increasing need for replacing tests conducted on animals, continuous advancements in microfluidics and tissue engineering, rising focus on personalized medicine and drug development, and surging need for cost-effective and faster drug screening models, among other contributing factors.
The growing global burden of chronic diseases, such as cardiovascular disorders, malignancies, diabetes, and respiratory conditions, is a major contributor to the market as they require more sophisticated and tailored drug testing, as well as disease modeling tools. There is a global increase in these conditions which has resulted in mitigating the need for more advanced research tools like organs-on-chips (OoC) which can simulate human organ in vitro to advance the research infrastructure. According to the World Health Organization (WHO), noncommunicable diseases (NCDs) kill 41 million people each year, equivalent to 74% of all deaths globally. Each year, more than 15 million people die from NCD between the ages of 30 and 69 years; 85% of these premature deaths occur in low- and middle-income countries.
Moreover, the increasing need for personalized medicine also contributes greatly to the development of organs-on-chips (OoC) technologies, as these systems provide tailored analyses of drug responses, patient-specific disease mechanisms, and acute individualizations. Personalized medicine endeavors to optimize the treatment strategy to the patient’s genetic and molecular characteristics, and OoCs are far better than customary in vitro models since they replicate human organ functions more accurately.
Organ-on-chips (OoCs) are advanced microfluidic devices capable of recreating the form and function of human organs at a small scale using human cells cultured in controlled conditions. These chips mimic physical behaviors including blood circulation, mechanical pressure, and cellular activities, enabling precise studies of organ functions, disease progression, and the impact of drugs on the body. Organ-on-chip technology provides a novel approach to replace testing on living organisms, granting a more pertinent platform for testing drugs, assessing their toxicity, and conducting biomedical research, which may improve precision while decreasing expenditures.
Organ-on-chips Market Trends
The organ-on-chips (OoC) market is witnessing emerging trends which expand its usage and accelerating its adoption in research and development. Primarily due to the ever-growing technology on artificial intelligence in healthcare and machine learning, organ-on-chip technology is rapidly advancing. Automated systems are now able to deliver thorough analysis of the complex cellular antics to microminiature organ systems, making it easier for scientist to evaluate and make predictions on the effects of certain drug procedures on the systems.
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Organ-on-chips Market Analysis
Based on type, the market is classified into products and services. The products segment is further bifurcated into liver-on-chip, lung-on-chip, heart-on-chip, kidney-on-chip, and other products. The products segment generated the highest revenue of USD 110.8 million in 2024.
Based on material, the organ-on-chips market is classified into polydimethylsiloxane (PDMS), polymer glass, and other materials. The polydimethylsiloxane (PDMS) segment dominated the market in 2023 with a market share of 42.9%.
Based on model type, the organ-on-chips market is segmented into single organ model and multi-organ model. The single organ model segment dominated the market in 2024 and is anticipated to reach USD 1.1 billion by the end of forecast period.
Based on application, the organ-on-chips market is segmented into drug discovery, disease modelling, toxicity testing, personalized medicine, and other applications. The drug discovery segment dominated the market in 2024 and is anticipated to reach USD 657.3 million by the end of forecast period.
Based on end use, the organ-on-chips market is segmented into pharmaceutical and biotechnology companies, academic and research institutes, and other end users. The pharmaceutical and biotechnology companies segment dominated the market in 2024 and is anticipated to reach USD 1.4 billion by the end of forecast period.
U.S. organ-on-chips market accounted for USD 56.9 million in 2024. The U.S. dominated the global market in 2023 with USD 42.6 million growing from USD 30.8 million in 2022 and is anticipated to grow at a CAGR of 28.6% between 2025 to 2034 period.
UK organ-on-chips market in the Europe is projected to grow remarkably in the coming years.
China holds a dominant position in the Asia Pacific organ-on-chips market.
Brazil organ-on-chips market in the Latin America is projected to grow remarkably in the coming years.
Organ-on-chips Market Share
The key players in the market such as Emulate, Axosim, TissUse GmbH, MIMETAS, and Nortis Inc., account for approximately 60% of the total market share, underscoring their strong influence on the organ-on-chips (OoC) landscape. The market is marked by rapid technological advancements and frequent new product introductions aimed at enhancing physiological relevance and research efficiency. Pharmaceutical companies and research institutions are increasingly integrating OoC devices into their workflows to improve the accuracy of drug discovery, accelerate preclinical testing, and reduce the high costs associated with failure in traditional models. Furthermore, the rising focus on personalized medicine is driving demand for customized OoC systems that reflect individual patient biology, further expanding the market’s scope.
Organ-on-chips Market Companies
Prominent players operating in the organ-on-chips industry include:
Organ-on-chips industry News
The organ-on-chips market research report includes an in-depth coverage of the industry with estimates and forecast in terms of revenue in USD Million and from 2021 – 2034 for the following segments:
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Market, By Type
Market, By Material
Market, By Model Type
Market, By Application
Market, By End Use
The above information is provided for the following regions and countries: